Description
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Osteoarthritis of the knee (OA knee) is a common, chronic, progressive, skeletal, degenerative disorder. Despite continued physiotherapy and wide use of nonsteroidalanti-inflammatory drugs (NSAIDs), this diseases of concern since it affects the mobility of individuals and their quality of life. The NSAIDs mainlyact by blocking prostaglandin synthesis. The other mediators of inflammation like leukotrines and complement pathways are not influenced by the NSAIDs.
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